yabause.org/2013/01/23/yabause-0-9-12/

Now has a Cocoa port with ISO and cue/bin support

Awesome. I love their regularly-irregular not dead yet update cycle.

They weren't kidding about about the OpenGL video option being more unstable.

First time ever OS X itself has crashed on my iMac.
Tried a second time, didn't crash OS, but no output and Yabause crashed on exit.

Software video options seems to be working OK though.

Sounds an awful lot like PCSX-Reloaded's OpenGL mode - Crashtastic and unstable, yet software works fine. Shame too - OpenGL mode makes the games look a lot nicer, especially pixel salads like FF VIII and FF IX.